CatDog has been referenced in popular culture several times.
Animation Domination High-DefEdit
- An episode of Scientifically Accurate from Animation Domination High-Def Shorts parodies CatDog. It is about an artificially merged Cat and Dog that are . The Theme Song is also parodied, as well as Nickelodeon.
- In the episode "Friends of Peter G", Peter Griffin sings the theme song, though with some mumbling.
- In the episode "Weighing Harold", CatDog can be seen in the shelf of the comic book store Arnold visits.